Detailed information for IMPDH1
Basic information
| Official symbol | IMPDH1 |
|---|---|
| Official full name | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| Location | 7q31.3-q32 |
| Gene type | protein-coding |
| Synonyms | IMPD|IMPD1|LCA11|RP10|sWSS2608 |
| Quick links | Entrez ID:3614; HGNC:6052; MIM:146690; Ensembl:ENSG00000106348; HPRD:08853; Vega:OTTHUMG00000157713 |
GO related
| GO term accession | GO term name | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-Value |
|---|---|---|---|---|---|---|---|
| GO:0005488 | binding | 11955 | 150 | 132.97 | 1.13 | 0.0005 | 0.0090 |
Pathway related
| Term | Surce | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|---|---|---|---|---|---|---|
| Purine metabolism | KEGG | 162 | 7 | 0.73 | 9.61 | 9.46e-06 | 0.0001 |
PPI related
| ID | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|
OMIM related
| chromosome | begin | end | disorder MIM number | disorder | phene mapping key | gene/locus MIM number | cytogenetic loaction |
|---|---|---|---|---|---|---|---|
| chr7 | 128031330 | 128051036 | 613837 | Leber congenital amaurosis 11 | 3 | 146690 | 7q32.1 |
| chr7 | 128031330 | 128051036 | 180105 | Retinitis pigmentosa 10 | 3 | 146690 | 7q32.1 |
MGI related
| chromosome | begin | end | gene ID | gene symbol of mouse | MGI | MP | phenotype description |
|---|---|---|---|---|---|---|---|
| chr7 | 128031330 | 128051036 | 3614 | Impdh1 | MGI:96567 | MP:0005384 | cellular phenotype |
| chr7 | 128031330 | 128051036 | 3614 | Impdh1 | MGI:96567 | MP:0005387 | immune system phenotype |
| chr7 | 128031330 | 128051036 | 3614 | Impdh1 | MGI:96567 | MP:0005397 | hematopoietic system phenotype |
Mutation spectrum
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Gene-disease network
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