Detailed information for ADAMTS18
Basic information
| Official symbol | ADAMTS18 |
|---|---|
| Official full name | ADAM metallopeptidase with thrombospondin type 1 motif, 18 |
| Location | 16q23 |
| Gene type | protein-coding |
| Synonyms | ADAMTS21|KNO2 |
| Quick links | Entrez ID:170692; HGNC:17110; MIM:607512; Ensembl:ENSG00000140873; HPRD:06333; Vega:OTTHUMG00000137619 |
GO related
| GO term accession | GO term name | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-Value |
|---|---|---|---|---|---|---|---|
| GO:0005488 | binding | 11955 | 150 | 132.97 | 1.13 | 0.0005 | 0.0090 |
| GO:0005578 | proteinaceous extracellular matrix | 360 | 14 | 3.93 | 3.57 | 4.22e-05 | 0.0002 |
| GO:0031012 | extracellular matrix | 426 | 15 | 4.65 | 3.23 | 6.94e-05 | 0.0004 |
Pathway related
| Term | Surce | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|
PPI related
| ID | Number of reference genes | Number of genes | Expected number | Ratio of enrichment | P-value | Adjusted P-value |
|---|
OMIM related
| chromosome | begin | end | disorder MIM number | disorder | phene mapping key | gene/locus MIM number | cytogenetic loaction |
|---|---|---|---|---|---|---|---|
| chr16 | 77315024 | 77470011 | 608454 | Knobloch syndrome 2 | 3 | 607512 | 16q23.1 |
MGI related
| chromosome | begin | end | gene ID | gene symbol of mouse | MGI | MP | phenotype description |
|---|---|---|---|---|---|---|---|
| chr16 | 77315024 | 77470011 | 170692 | Adamts18 | MGI:2442600 | MP:0005389 | reproductive system phenotype |
Mutation spectrum
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Gene-disease network
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